Gary Marcus

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Score 57
Gary Marcus
@GaryMarcus
·
271d
This looks like great new work but “paste sequence -> make drug” is misleading.

It is more like:

Paste sequence, get a candidate drug.

Then start the arduous process of seeing whether drug works in animals and then humans and does so without serious side effects.
9/9/2024, 11:53:30 PM
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In reply to:
Alex Kaplan
@alexkaplan0
·
271d
Huge news today. This is the ChatGPT moment for drug discovery.

Chai-1 is a new open source foundation model that outperforms AlphaFold3 and ESM3 for molecular structure prediction.

Basically, paste sequence -> make drug. Check this out: (1/6)
Joshua Meier
@joshim5
·
271d
We’re excited to introduce @ChaiDiscovery and release Chai-1, a foundation model for molecular structure prediction that performs at the state-of-the-art across a variety of drug discovery tasks

We're releasing inference code, weights & a web interface: https://www.chaidiscovery.com/bl…

The statement 'Some important caveats' by @alexkaplan0 in response to the conversation about Chai-1 and its capabilities in drug discovery constitutes public discourse. It engages with a significant public issue, namely the development and implications of AI in drug discovery. The statement aims to provide a more nuanced understanding of the technology's capabilities and limitations.

  1. Principle 1:
    I will strive to do no harm with my words and actions.
    The statement strives to do no harm by clarifying potential misconceptions about the technology, which is important in preventing unrealistic expectations. [+1]
  2. Principle 3:
    I will use my words and actions to promote understanding, empathy, and compassion.
    The statement promotes understanding by highlighting the complexities involved in drug discovery, thus fostering a more informed and realistic perspective. [+1]
  3. Principle 4:
    I will engage in constructive criticism and dialogue with those in disagreement and will not engage in personal attacks or ad hominem arguments.
    The statement engages in constructive dialogue by addressing a point made by another user (@GaryMarcus) and adding to the conversation without resorting to personal attacks. [+1]